Krista Vernoff, a former Omega Seasonal Staff member, is an Emmy-nominated television writer best known for the Golden Globe-winning work on Grey’s Anatomy and the dark comedy Shameless. Much of Vernoff's work has been in the medium of television, and she has worked on a number of shows, including, Charmed, Wonderfalls, Law & Order, and Private Practice, as well as her work for Grey's Anatomy, for which she was nominated for a Best Writing Emmy Award.

Vernoff took her first writing class at Omega Institute while working as summer staff. Since then she has gone on to Emmy nominations and a Golden Globe win for her work as a television writer. She’s also a writer of songs, plays, screenplays, essays, and The Game On Diet, which is part comic memoir and part health instructional. Her writing philosophy is consistent across all these mediums: "Tell the truth. Bare your soul. Laugh while you do it."

Krista Vernoff is credited with the introduction of the catchphrase "seriously" into the dialogue of Grey's Anatomy episodes. She is also a playwright. A production of her play Me, My Guitar, and Don Henley opened in October 2006 in an off-Broadway theater.